DHDH antibody (Middle Region)

Catalog No. ABIN2786036

The Rabbit Polyclonal anti-DHDH antibody is suitable to detect DHDH in samples from Human, Cow, Dog, Horse, Pig and Saccharomyces cerevisiae. It has been validated for WB.

Quick Overview for DHDH antibody (Middle Region) (ABIN2786036)

Target: DHDH (Dihydrodiol Dehydrogenase (Dimeric) (DHDH))

Reactivity: Human, Cow, Dog, Horse, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHDH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DHDH Antibody

Binding Specificity: Middle Region

Purpose: DHDH Antibody - middle region

Sequence: PCWCPTELVV KGEHKEFPLP PVPKDCNFDN GAGMSYEAKH VWECLRKGMK

Predicted Reactivity: Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Pig: 85%, Yeast: 90%

Characteristics: This is a rabbit polyclonal antibody against DHDH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DHDH

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55066-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DHDH

Target: DHDH (Dihydrodiol Dehydrogenase (Dimeric) (DHDH))

Alternative Name: DHDH

Background:

Background Information: DHDH is an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction.This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction.

Gene Name: Dihydrodiol dehydrogenase (dimeric)

Alternative Symbols: 2DD, HUM2DD

Protein Name: Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

Molecular Weight: 36kDa

Gene ID: 27294

NCBI Accession: NP_055290

UniProt: Q9UQ10