SAPS1 antibody (N-Term)

Catalog No. ABIN2786061

The Rabbit Polyclonal anti-SAPS1 antibody (ABIN2786061) specifically detects SAPS1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit and Dog samples.

Quick Overview for SAPS1 antibody (N-Term) (ABIN2786061)

Target: SAPS1 (SAPS Domain Family, Member 1 (SAPS1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAPS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SAPS1 Antibody

Binding Specificity: N-Term

Purpose: PPP6R1 Antibody - N-terminal region

Sequence: MFWKFDLHTS SHLDTLLERE DLSLPELLDE EDVLQECKVV NRKLLDFLLQ

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SAPS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPP6R1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55109-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SAPS1

Target: SAPS1 (SAPS Domain Family, Member 1 (SAPS1))

Alternative Name: PPP6R1

Background:

Background Information: Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C, MIM 300141) (Stefansson and Brautigan, 2006 [PubMed 16769727]).

Gene Name: Protein phosphatase 6, regulatory subunit 1

Alternative Symbols: PP6R1, SAPS1, SAP190, KIAA1115

Protein Name: Serine/threonine-protein phosphatase 6 regulatory subunit 1

Molecular Weight: 97kDa

Gene ID: 22870

NCBI Accession: NP_055746

UniProt: Q9UPN7