CMTR1 antibody (C-Term)

Catalog No. ABIN2786076

The Rabbit Polyclonal anti-CMTR1 antibody is suitable to detect CMTR1 in samples from Human, Mouse, Dog, Guinea Pig, Rabbit, Rat, Cow, Horse, Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for CMTR1 antibody (C-Term) (ABIN2786076)

Target: CMTR1 (Cap Methyltransferase 1 (CMTR1))

Reactivity: Human, Mouse, Dog, Guinea Pig, Rabbit, Rat, Cow, Horse, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CMTR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CMTR1 Antibody

Binding Specificity: C-Term

Purpose: FTSJD2 Antibody - C-terminal region

Sequence: YRLEEMEKIF VRLEMKIIKG SSGTPKLSYT GRDDRHFVPM GLYIVRTVNE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FTSJD2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FTSJD2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55152-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CMTR1

Target: CMTR1 (Cap Methyltransferase 1 (CMTR1))

Alternative Name: FTSJD2

Background:

Background Information: FTSJD2 is a S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. It methylates the ribose of the first nucleotide of a m7GpppG-capped mRNA to produce m7GpppNmp (cap1). Cap1 modification is linked to higher levels of translation. It may be involved in the interferon response pathway.

Gene Name: FtsJ methyltransferase domain containing 2

Alternative Symbols: MTr1, hMTr1, FTSJD2, KIAA0082

Protein Name: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1

Molecular Weight: 95kDa

Gene ID: 23070

NCBI Accession: NP_055865

UniProt: Q8N1G2