HISPPD1 antibody (Middle Region)

Catalog No. ABIN2786093

The Rabbit Polyclonal anti-HISPPD1 antibody (ABIN2786093) specifically detects HISPPD1 in WB. The antibody is reactive with Human, Mouse, Dog, Guinea Pig, Cow, Horse, Rat and Rabbit samples.

Quick Overview for HISPPD1 antibody (Middle Region) (ABIN2786093)

Target: HISPPD1 (PPIP5K2) (diphosphoinositol Pentakisphosphate Kinase 2 (PPIP5K2))

Reactivity: Human, Mouse, Dog, Guinea Pig, Cow, Horse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HISPPD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HISPPD1 Antibody

Binding Specificity: Middle Region

Purpose: HISPPD1 Antibody - middle region

Sequence: SLSSCQQRVK ARLHEILQKD RDFTAEDYEK LTPSGSISLI KSMHLIKNPV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HISPPD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HISPPD1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55203-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HISPPD1

Target: HISPPD1 (PPIP5K2) (diphosphoinositol Pentakisphosphate Kinase 2 (PPIP5K2))

Alternative Name: HISPPD1

Background:

Background Information: Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively.Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]).[supplied by OMIM].

Gene Name: Diphosphoinositol pentakisphosphate kinase 2

Alternative Symbols: VIP2, IP7K2, CFAP160, DFNB100, HISPPD1

Protein Name: Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

Molecular Weight: 138kDa

Gene ID: 23262

NCBI Accession: NP_056031

UniProt: O43314

Pathways: Inositol Metabolic Process