ACOT11 antibody (Middle Region)

Catalog No. ABIN2786125

This Rabbit Polyclonal antibody specifically detects ACOT11 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig and Rabbit.

Quick Overview for ACOT11 antibody (Middle Region) (ABIN2786125)

Target: ACOT11 (Acyl-CoA Thioesterase 11 (ACOT11))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOT11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACOT11 Antibody

Binding Specificity: Middle Region

Purpose: ACOT11 Antibody - middle region

Sequence: YVIALRSVTL PTHRETPEYR RGETLCSGFC LWREGDQLTK CCWVRVSLTE

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ACOT11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACOT11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55281-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACOT11

Target: ACOT11 (Acyl-CoA Thioesterase 11 (ACOT11))

Alternative Name: ACOT11

Background:

Background Information: ACOT11 is a protein with acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Expression of a similar murine protein in brown adipose tissue is induced by cold exposure and repressed by warmth. Expression of the mouse protein has been associated with obesity, with higher expression found in obesity-resistant mice compared with obesity-prone mice.This gene encodes a protein with acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Expression of a similar murine protein in brown adipose tissue is induced by cold exposure and repressed by warmth. Expression of the mouse protein has been associated with obesity, with higher expression found in obesity-resistant mice compared with obesity-prone mice. Alternative splicing results in two transcript variants encoding different isoforms.

Gene Name: Acyl-CoA thioesterase 11

Alternative Symbols: BFIT, THEA, THEM1, STARD14

Protein Name: Acyl-coenzyme A thioesterase 11

Molecular Weight: 68kDa

Gene ID: 26027

NCBI Accession: NP_056362

UniProt: Q8WXI4