Kallikrein 13 antibody (Middle Region)

Catalog No. ABIN2786133

Product Details anti-Kallikrein 13 Antibody

Target: Kallikrein 13 (KLK13) (Kallikrein-Related Peptidase 13 (KLK13))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Dog, Rat, Horse, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 13 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VLTAAHCLKE GLKVYLGKHA LGRVEAGEQV REVVHSIPHP EYRRSPTHLN

Predicted Reactivity: Cow: 79%, Dog: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against KLK13. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KLK13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 277 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Kallikrein 13

Target: Kallikrein 13 (KLK13) (Kallikrein-Related Peptidase 13 (KLK13))

Alternative Name: KLK13 (KLK13 Products)

Synonyms: KLK-L4 antibody, KLKL4 antibody, Egfbp-2 antibody, mGk-13 antibody, kallikrein related peptidase 13 antibody, kallikrein related-peptidase 13 antibody, KLK13 antibody, Klk13 antibody

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined.
Alias Symbols: DKFZP586J1923, KLK-L4, KLKL4
Protein Interaction Partner: SERPINF2, SERPINA1, A2M,
Protein Size: 277

Molecular Weight: 29 kDa

Gene ID: 26085

NCBI Accession: NM_015596, NP_056411

UniProt: Q9UKR3

Pathways: Complement System