MKNK2 antibody (N-Term)

Catalog No. ABIN2786162

This Rabbit Polyclonal antibody specifically detects MKNK2 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow and Rabbit.

Quick Overview for MKNK2 antibody (N-Term) (ABIN2786162)

Target: MKNK2 (MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKNK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MKNK2 Antibody

Binding Specificity: N-Term

Sequence: SDFGLQCSAR PDMPASQPID IPDAKKRGKK KKRGRATDSF SGRFEDVYQL

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MKNK2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MKNK2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 465 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MKNK2

Target: MKNK2 (MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2))

Alternative Name: MKNK2

Background: MKNK2 may play a role in the response to environmental stress and cytokines. It appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Alias Symbols: GPRK7, MNK2
Protein Interaction Partner: MAPK14, MAPK8, RBX1, CUL2, VHL, VBP1, ELAVL1, UBC, RPL7A, MKNK2, ESR2, MAPK1, EIF4E, ESR1, EIF4G1,
Protein Size: 465

Molecular Weight: 51 kDa

Gene ID: 2872

NCBI Accession: NM_199054, NP_951009

UniProt: Q9HBH9

Pathways: MAPK Signaling