MKNK2 antibody (N-Term)

Catalog No. ABIN2786162

Product Details anti-MKNK2 Antibody

Target: MKNK2 (MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKNK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SDFGLQCSAR PDMPASQPID IPDAKKRGKK KKRGRATDSF SGRFEDVYQL

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MKNK2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MKNK2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 465 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MKNK2

Target: MKNK2 (MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2))

Alternative Name: MKNK2 (MKNK2 Products)

Background: MKNK2 may play a role in the response to environmental stress and cytokines. It appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Alias Symbols: GPRK7, MNK2
Protein Interaction Partner: MAPK14, MAPK8, RBX1, CUL2, VHL, VBP1, ELAVL1, UBC, RPL7A, MKNK2, ESR2, MAPK1, EIF4E, ESR1, EIF4G1,
Protein Size: 465

Molecular Weight: 51 kDa

Gene ID: 2872

NCBI Accession: NM_199054, NP_951009

UniProt: Q9HBH9

Pathways: MAPK Signaling