GSPT2 antibody (N-Term)

Catalog No. ABIN2786165

This Rabbit Polyclonal antibody specifically detects GSPT2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse and Pig.

Quick Overview for GSPT2 antibody (N-Term) (ABIN2786165)

Target: GSPT2 (G1 To S Phase Transition 2 (GSPT2))

Reactivity: Human, Mouse, Rat, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSPT2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GSPT2 Antibody

Binding Specificity: N-Term

Purpose: GSPT2 Antibody - N-terminal region

Sequence: MALEESWEHS KEVSEAEPGG GSSGDSGPPE ESGQEMMEEK EEIRKSKSVI

Predicted Reactivity: Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against GSPT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSPT2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55356-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GSPT2

Target: GSPT2 (G1 To S Phase Transition 2 (GSPT2))

Alternative Name: GSPT2

Background:

Targeted Subunit: ERF3B

Background Information: GSPT2 is closely related to GSPT1, a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1, functions as a polypeptide chain release factor.GSPT2 is closely related to GSPT1 (MIM 139259), a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1 (MIM 600285), functions as a polypeptide chain release factor.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-207 BC036077.1 1-207 208-1527 AJ251548.1 12-1331 1528-2497 AK001303.1 1512-2481 2498-2503 AK023155.1 2487-2492

Gene Name: G1 to S phase transition 2

Alternative Symbols: GST2, ERF3B

Protein Name: Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

Molecular Weight: 69kDa

Gene ID: 23708

NCBI Accession: NP_060564

UniProt: Q8IYD1