GSPT2 antibody (Middle Region)

Catalog No. ABIN2786166

The Rabbit Polyclonal anti-GSPT2 antibody (ABIN2786166) specifically detects GSPT2 in WB. The antibody is reactive with Human, Mouse, Rat, Horse, Pig, Dog, Cow, Guinea Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for GSPT2 antibody (Middle Region) (ABIN2786166)

Target: GSPT2 (G1 To S Phase Transition 2 (GSPT2))

Reactivity: Human, Mouse, Rat, Horse, Pig, Dog, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSPT2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GSPT2 Antibody

Binding Specificity: Middle Region

Purpose: GSPT2 Antibody - middle region

Sequence: GANIKEQSDF CPWYTGLPFI PYLDNLPNFN RSIDGPIRLP IVDKYKDMGT

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GSPT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GSPT2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55357-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GSPT2

Target: GSPT2 (G1 To S Phase Transition 2 (GSPT2))

Alternative Name: GSPT2

Background:

Targeted Subunit: ERF3B

Background Information: GSPT2 is closely related to GSPT1, a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1, functions as a polypeptide chain release factor.

Gene Name: G1 to S phase transition 2

Alternative Symbols: GST2, ERF3B

Protein Name: Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

Molecular Weight: 69kDa

Gene ID: 23708

NCBI Accession: NP_060564

UniProt: Q8IYD1