PDE7B antibody (Middle Region)

Catalog No. ABIN2786168

This Rabbit Polyclonal antibody specifically detects PDE7B in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse and Zebrafish (Danio rerio).

Quick Overview for PDE7B antibody (Middle Region) (ABIN2786168)

Target: PDE7B (phosphodiesterase 7B (PDE7B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE7B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE7B Antibody

Binding Specificity: Middle Region

Purpose: PDE7B Antibody - middle region

Sequence: IGMLRESRLL AHLPKEMTQD IEQQLGSLIL ATDINRQNEF LTRLKAHLHN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against PDE7B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDE7B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55364-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE7B

Target: PDE7B (phosphodiesterase 7B (PDE7B))

Alternative Name: PDE7B

Background:

Background Information: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates a

Gene Name: Phosphodiesterase 7B

Alternative Symbols: bA472E5.1

Protein Name: cAMP-specific 3',5'-cyclic phosphodiesterase 7B

Molecular Weight: 52kDa

Gene ID: 27115

NCBI Accession: NP_061818

UniProt: Q9NP56

Pathways: cAMP Metabolic Process