DAGLB antibody (Middle Region)

Catalog No. ABIN2786205

The Rabbit Polyclonal anti-DAGLB antibody is suitable to detect DAGLB in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio) and Horse. It has been validated for WB.

Quick Overview for DAGLB antibody (Middle Region) (ABIN2786205)

Target: DAGLB (Diacylglycerol Lipase, beta (DAGLB))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAGLB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DAGLB Antibody

Binding Specificity: Middle Region

Purpose: DAGLB Antibody - middle region

Sequence: STAELFSTYF SDTDLVPSDI AAGLALLHQQ QDNIRNNQEP AQVVCHAPGS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against DAGLB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DAGLB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55430-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DAGLB

Target: DAGLB (Diacylglycerol Lipase, beta (DAGLB))

Alternative Name: DAGLB

Background:

Background Information: DAGLB belongs to the AB hydrolase superfamily.It catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. This protein is required for axonal growth during development and for retrograde synaptic signaling at mature synapses.

Gene Name: Diacylglycerol lipase, beta

Alternative Symbols: KCCR13L, DAGLBETA

Protein Name: Sn1-specific diacylglycerol lipase beta

Molecular Weight: 74kDa

Gene ID: 221955

NCBI Accession: NP_631918

UniProt: Q8NCG7