SENP5 antibody (Middle Region)

Catalog No. ABIN2786236

The Rabbit Polyclonal anti-SENP5 antibody has been validated for WB. It is suitable to detect SENP5 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for SENP5 antibody (Middle Region) (ABIN2786236)

Target: SENP5 (SUMO1/sentrin Specific Peptidase 5 (SENP5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SENP5 Antibody

Binding Specificity: Middle Region

Sequence: LSGFLDEVMK KYGSLVPLSE KEVLGRLKDV FNEDFSNRKP FINREITNYR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SENP5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SENP5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 755 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SENP5

Target: SENP5 (SUMO1/sentrin Specific Peptidase 5 (SENP5))

Alternative Name: SENP5

Background: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1, MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates.
Alias Symbols: DKFZp564O1016, FLJ42398, MGC27076
Protein Interaction Partner: RABGAP1, SUMO3, PASK, SUMO2,
Protein Size: 755

Molecular Weight: 87 kDa

Gene ID: 205564

NCBI Accession: NM_152699, NP_689912

UniProt: Q96HI0