MFSD8 antibody (Middle Region)

Catalog No. ABIN2786259

The Rabbit Polyclonal anti-MFSD8 antibody is suitable to detect MFSD8 in samples from Human, Mouse, Rabbit, Rat, Cow, Dog, Guinea Pig and Horse. It has been validated for WB.

Quick Overview for MFSD8 antibody (Middle Region) (ABIN2786259)

Target: MFSD8 (Major Facilitator Superfamily Domain Containing 8 (MFSD8))

Reactivity: Human, Mouse, Rabbit, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MFSD8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MFSD8 Antibody

Binding Specificity: Middle Region

Purpose: MFSD8 Antibody - middle region

Sequence: FFILLPWGNQ FPKIQWEDLH NNSIPNTTFG EIIIGLWKSP MEDDNERPTG

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MFSD8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MFSD8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55547-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MFSD8

Target: MFSD8 (Major Facilitator Superfamily Domain Containing 8 (MFSD8))

Alternative Name: MFSD8

Background:

Background Information: This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL).

Gene Name: Major facilitator superfamily domain containing 8

Alternative Symbols: CCMD, CLN7

Protein Name: Major facilitator superfamily domain-containing protein 8

Molecular Weight: 57kDa

Gene ID: 256471

NCBI Accession: NP_689991

UniProt: Q8NHS3