GCET2 antibody (Middle Region)

Catalog No. ABIN2786263

This Rabbit Polyclonal antibody specifically detects GCET2 in WB. It exhibits reactivity toward Human.

Quick Overview for GCET2 antibody (Middle Region) (ABIN2786263)

Target: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCET2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GCET2 Antibody

Binding Specificity: Middle Region

Purpose: GCET2 Antibody - middle region

Sequence: YSLLHMPSTD PRHARSPEDE YELLMPHRIS SHFLQQPRPL MAPSETQFSH

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GCET2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GCET2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55553-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GCET2

Target: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Alternative Name: GCET2

Background:

Background Information: GCET2 is a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4.This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: Germinal center expressed transcript 2

Alternative Symbols: HGAL, GCAT2, GCET2

Protein Name: Germinal center-associated signaling and motility protein

Molecular Weight: 21kDa

Gene ID: 257144

NCBI Accession: NP_689998

UniProt: Q8N6F7