APBB2 antibody (Middle Region)

Catalog No. ABIN2786292

Cited in 1 publication. The Rabbit Polyclonal anti-APBB2 antibody (ABIN2786292) specifically detects APBB2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit and Pig samples.

Quick Overview for APBB2 antibody (Middle Region) (ABIN2786292)

Target: APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APBB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APBB2 Antibody

Binding Specificity: Middle Region

Purpose: APBB2 Antibody - middle region

Sequence: QNLAPSDEES SWTTLSQDSA SPSSPDETDI WSDHSFQTDP DLPPGWKRVS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against APBB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human APBB2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55624-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-APBB2 antibody (ABIN2786292)

Hong, Hsu, Schultz, Pratt, Mattison, Chang: "Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response." in: BMC molecular biology, Vol. 8, pp. 50, (2007) (PubMed).

Target Details for APBB2

Target: APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))

Alternative Name: APBB2

Background:

Background Information: APBB2 may modulate the internalization of beta-amyloid precursor protein.The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction.

Gene Name: Amyloid beta (A4) precursor protein-binding, family B, member 2

Alternative Symbols: FE65L, FE65L1

Protein Name: Amyloid beta A4 precursor protein-binding family B member 2

Molecular Weight: 81kDa

Gene ID: 323

NCBI Accession: NP_775098

UniProt: Q92870