ERAS antibody (Middle Region)

Catalog No. ABIN2786373

This Rabbit Polyclonal antibody specifically detects ERAS in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig and Pig.

Quick Overview for ERAS antibody (Middle Region) (ABIN2786373)

Target: ERAS (ES cell expressed Ras (ERAS))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERAS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERAS Antibody

Binding Specificity: Middle Region

Purpose: ERAS Antibody - middle region

Sequence: AQPLVLVGNK CDLVTTAGDA HAAAAALAHS WGAHFVETSA KTRQGVEEAF

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ERAS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ERAS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55794-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ERAS

Target: ERAS (ES cell expressed Ras (ERAS))

Alternative Name: ERAS

Background:

Background Information: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. ERAS plays an important role in the tumor-like growth properties of embryonic stem cells.

Gene Name: ES cell expressed Ras

Alternative Symbols: HRAS2, HRASP

Protein Name: GTPase ERas

Molecular Weight: 25kDa

Gene ID: 3266

NCBI Accession: NP_853510

UniProt: Q7Z444