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FBXO33 antibody (Middle Region)

FBXO33 Reactivity: Rat, Human, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786447
  • Target See all FBXO33 Antibodies
    FBXO33 (F-Box Protein 33 (FBXO33))
    Binding Specificity
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Rat, Human, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 20
    • 3
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXO33 antibody is un-conjugated
    Application
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    Western Blotting (WB)
    Sequence
    VIDTSGFPDL SDNRNEDPLV LLAWRCTKLS LLAIHGYTVW AHNLIAIARL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against FBXO33. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human FBXO33
    Top Product
    Discover our top product FBXO33 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 555 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FBXO33 (F-Box Protein 33 (FBXO33))
    Alternative Name
    FBXO33 (FBXO33 Products)
    Synonyms
    FBXO33 antibody, BMND12 antibody, Fbx33 antibody, c14_5247 antibody, 5730501N20Rik antibody, AI642135 antibody, F-box protein 33 antibody, F-box protein 33 S homeolog antibody, FBXO33 antibody, fbxo33 antibody, fbxo33.S antibody, Fbxo33 antibody
    Background
    FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
    Alias Symbols: Fbx33, c14_5247, BMND12
    Protein Interaction Partner: CUL1, YBX1, UBC,
    Protein Size: 555
    Molecular Weight
    62 kDa
    Gene ID
    254170
    NCBI Accession
    NM_203301, NP_976046
    UniProt
    Q7Z6M2
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