ALOX15 antibody (Middle Region)

Catalog No. ABIN2786489

This Rabbit Polyclonal antibody specifically detects ALOX15 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Pig, Rabbit and Cow.It has been mentioned in 1 publication

Quick Overview for ALOX15 antibody (Middle Region) (ABIN2786489)

Target: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALOX15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALOX15 Antibody

Binding Specificity: Middle Region

Purpose: ALOX15 Antibody - middle region

Sequence: QHASVHLGQL DWYSWVPNAP CTMRLPPPTT KDATLETVMA TLPNFHQASL

Predicted Reactivity: Cow: 92%, Dog: 93%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against ALOX15. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALOX15

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56030-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-ALOX15 antibody (ABIN2786489)

Wieczfinska, Kacprzak, Pospiech, Sokolowska, Nowakowska, Pniewska, Bednarek, Kuprys-Lipinska, Kuna, Pawliczak: "The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge." in: Respiratory research, Vol. 16, pp. 147, (2015) (PubMed).

Target Details for ALOX15

Target: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Alternative Name: ALOX15

Background:

Background Information: ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. ALOX15 also acts on C-12 of arachidonate as well as on linoleic acid.

Gene Name: Arachidonate 15-lipoxygenase

Alternative Symbols: LOG15, 12-LOX, 15-LOX, 15-LOX-1

Protein Name: Arachidonate 15-lipoxygenase

Molecular Weight: 73kDa

Gene ID: 246

NCBI Accession: NP_001131

UniProt: P16050

Pathways: Regulation of Actin Filament Polymerization