PEPD antibody (Middle Region)

Catalog No. ABIN2786507

Cited in 1 publication. The Rabbit Polyclonal anti-PEPD antibody (ABIN2786507) specifically detects PEPD in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow and Goat samples.

Quick Overview for PEPD antibody (Middle Region) (ABIN2786507)

Target: PEPD (Peptidase D (PEPD))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEPD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PEPD Antibody

Binding Specificity: Middle Region

Sequence: LGAVFMPHGL GHFLGIDVHD VGGYPEGVER IDEPGLRSLR TARHLQPGMV

Predicted Reactivity: Cow: 92%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PEPD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PEPD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 493 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PEPD antibody (ABIN2786507)

Surazynski, Donald, Cooper, Whiteside, Salnikow, Liu, Phang: "Extracellular matrix and HIF-1 signaling: the role of prolidase." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 6, pp. 1435-40, (2008) (PubMed).

Target Details for PEPD

Target: PEPD (Peptidase D (PEPD))

Alternative Name: PEPD

Background: Xaa-Pro dipeptidase is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus (but not Pro-Pro). It is important in collagen metabolism because of the high levels of iminoacids.Xaa-Pro dipeptidase is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus (but not Pro-Pro). It is important in collagen metabolism because of the high levels of iminoacids. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-74 DC395475.1 1-74 75-101 DC385464.1 1-27 102-2018 BC015027.1 1-1917
Alias Symbols: MGC10905, PROLIDASE
Protein Interaction Partner: USP7, SUMO1, NDRG1, NAMPT, DPP3, CTSA, MVD, EIF6, GSR, GNS, GLS, GBP2, EIF5A, EIF4E, DLD, CASP7, CAPN1, ASS1, NHLRC2, LDHAL6B, FTO, BCCIP, CNDP2, GINS2, GDA, KYNU, RPS6KA1, SPP1, UBC, ATXN1, CUL2, TERF1, PEPD,
Protein Size: 493

Molecular Weight: 54 kDa

Gene ID: 5184

NCBI Accession: NM_000285, NP_000276

UniProt: P12955