PEPD antibody (Middle Region)
Quick Overview for PEPD antibody (Middle Region) (ABIN2786507)
Target
See all PEPD AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- LGAVFMPHGL GHFLGIDVHD VGGYPEGVER IDEPGLRSLR TARHLQPGMV
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Predicted Reactivity
- Cow: 92%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
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Characteristics
- This is a rabbit polyclonal antibody against PEPD. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PEPD
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 493 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Extracellular matrix and HIF-1 signaling: the role of prolidase." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 6, pp. 1435-40, (2008) (PubMed).
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: "Extracellular matrix and HIF-1 signaling: the role of prolidase." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 6, pp. 1435-40, (2008) (PubMed).
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- PEPD (Peptidase D (PEPD))
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Alternative Name
- PEPD
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Background
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Xaa-Pro dipeptidase is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus (but not Pro-Pro). It is important in collagen metabolism because of the high levels of iminoacids.Xaa-Pro dipeptidase is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus (but not Pro-Pro). It is important in collagen metabolism because of the high levels of iminoacids. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-74 DC395475.1 1-74 75-101 DC385464.1 1-27 102-2018 BC015027.1 1-1917
Alias Symbols: MGC10905, PROLIDASE
Protein Interaction Partner: USP7, SUMO1, NDRG1, NAMPT, DPP3, CTSA, MVD, EIF6, GSR, GNS, GLS, GBP2, EIF5A, EIF4E, DLD, CASP7, CAPN1, ASS1, NHLRC2, LDHAL6B, FTO, BCCIP, CNDP2, GINS2, GDA, KYNU, RPS6KA1, SPP1, UBC, ATXN1, CUL2, TERF1, PEPD,
Protein Size: 493 -
Molecular Weight
- 54 kDa
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Gene ID
- 5184
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NCBI Accession
- NM_000285, NP_000276
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UniProt
- P12955
Target
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