BLMH antibody (C-Term)

Catalog No. ABIN2786514

The Rabbit Polyclonal anti-BLMH antibody is suitable to detect BLMH in samples from Human, Rat, Mouse, Dog, Guinea Pig, Zebrafish (Danio rerio), Cow, Horse and Rabbit. It has been validated for WB.

Quick Overview for BLMH antibody (C-Term) (ABIN2786514)

Target: BLMH (Bleomycin Hydrolase (BLMH))

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Zebrafish (Danio rerio), Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLMH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BLMH Antibody

Binding Specificity: C-Term

Purpose: Blmh Antibody - C-terminal region

Sequence: GPITPLQFYK EHVKPLFNME DKICFVNDPR PQHKYNKLYT VDYLSNMVGG

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against Blmh. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Blmh

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56105-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BLMH

Target: BLMH (Bleomycin Hydrolase (BLMH))

Alternative Name: Blmh

Background:

Background Information: The encoded protein is a cytoplasmic cysteine peptidase involved in inactivation of bleomycin, a glycopeptide which is a component of combination chemotherapy regimens for cancer. This encoded enzyme is highly conserved, and it contains the signature active site residues of cysteine protease papain superfamily enzymes. It is postulated that this enzyme has protective effects against bleomycin-induced pulmonary fibrosis and bleomycin tumor resistance.

Alternative Symbols: Bh, Bmh, AI035728

Protein Name: Bleomycin hydrolase

Molecular Weight: 50kDa

Gene ID: 104184

NCBI Accession: NP_848760

UniProt: Q8R016