PCCB antibody (Middle Region)

Catalog No. ABIN2786521

The Rabbit Polyclonal anti-PCCB antibody is suitable to detect PCCB in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit and Sheep. It has been validated for WB.

Quick Overview for PCCB antibody (Middle Region) (ABIN2786521)

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCCB Antibody

Binding Specificity: Middle Region

Purpose: PCCB Antibody - middle region

Sequence: PGFLPGTAQE YGGIIRHGAK LLYAFAEATV PKVTVITRKA YGGAYDVMSS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PCCB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PCCB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56116-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCCB

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Alternative Name: PCCB

Background:

Background Information: PCCB is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. Defects in this gene are a cause of propionic acidemia type II (PA-2).

Gene Name: Propionyl CoA carboxylase, beta polypeptide

Alternative Symbols: DKFZp451E113

Protein Name: Propionyl-CoA carboxylase beta chain, mitochondrial

Molecular Weight: 58kDa

Gene ID: 5096

NCBI Accession: NP_000523

UniProt: P05166

Pathways: Monocarboxylic Acid Catabolic Process