PCCB antibody (Middle Region)

Catalog No. ABIN2786521

Product Details anti-PCCB Antibody

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PGFLPGTAQE YGGIIRHGAK LLYAFAEATV PKVTVITRKA YGGAYDVMSS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PCCB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PCCB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 539 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCCB

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Alternative Name: PCCB (PCCB Products)

Synonyms: 1300012P06Rik antibody, AI314687 antibody, R74805 antibody, propionyl-CoA carboxylase beta subunit antibody, propionyl Coenzyme A carboxylase, beta polypeptide antibody, PCCB antibody, Pccb antibody

Background: PCCB is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. Defects in this gene are a cause of propionic acidemia type II (PA-2).
Alias Symbols: DKFZp451E113
Protein Interaction Partner: HUWE1, PARK2, IFIT1, INPPL1, EPS15, UBE2N, UBC, EBNA-LP, ICT1, PCCB, PCCA,
Protein Size: 539

Molecular Weight: 58 kDa

Gene ID: 5096

NCBI Accession: NM_000532, NP_000523

UniProt: P05166

Pathways: Monocarboxylic Acid Catabolic Process