BLVRB antibody (Middle Region)

Catalog No. ABIN2786523

There is 1 publication for this product available. The Rabbit Polyclonal anti-BLVRB antibody is suitable to detect BLVRB in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow and Rabbit. It has been validated for WB.

Quick Overview for BLVRB antibody (Middle Region) (ABIN2786523)

Target: BLVRB (Flavin Reductase (BLVRB))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLVRB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BLVRB Antibody

Binding Specificity: Middle Region

Purpose: BLVRB Antibody - middle region

Sequence: GLKYVAVMPP HIGDQPLTGA YTVTLDGRGP SRVISKHDLG HFMLRCLTTD

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against BLVRB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BLVRB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56121-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-BLVRB antibody (ABIN2786523)

Clunie, Clark, Mortimer, Stephenson, Aitken, Smith, Sherwin, Archer: "Evaluating bone health in women with oestrogen receptor positive breast cancer (ERBC) starting aromatase inhibitors." in: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, Vol. 35, Issue 5, pp. 475-80, (2009) (PubMed).

Target Details for BLVRB

Target: BLVRB (Flavin Reductase (BLVRB))

Alternative Name: BLVRB

Background:

Background Information: BLVRB catalyzes electron transfer from reduced pyridine nucleotides to flavins as well as methylene blue, pyrroloquinoline quinone, riboflavin, or methemoglobin. BLVRB has possible role in protecting cells from oxidative damage or in regulating iron metabolism. In the liver, BLVRB converts biliverdin to bilirubin.

Gene Name: Biliverdin reductase B (flavin reductase (NADPH))

Alternative Symbols: FLR, BVRB, SDR43U1, HEL-S-10

Protein Name: Flavin reductase (NADPH)

Molecular Weight: 22kDa

Gene ID: 645

NCBI Accession: NP_000704

UniProt: P30043