PAIP2 antibody (N-Term)

Catalog No. ABIN2786594

This Rabbit Polyclonal antibody specifically detects PAIP2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig and Rabbit.

Quick Overview for PAIP2 antibody (N-Term) (ABIN2786594)

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAIP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAIP2 Antibody

Binding Specificity: N-Term

Purpose: PAIP2 Antibody - N-terminal region

Sequence: MKDPSRSSTS PSIINEDVII NGHSHEDDNP FAEYMWMENE EEFNRQIEEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PAIP2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56241-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAIP2

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Alternative Name: PAIP2

Background:

Background Information: PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.

Gene Name: Poly(A) binding protein interacting protein 2

Alternative Symbols: PAIP-2, PAIP2A

Protein Name: Polyadenylate-binding protein-interacting protein 2

Molecular Weight: 14kDa

Gene ID: 51247

NCBI Accession: NP_057564

UniProt: Q9BPZ3