Matrilin 3 antibody (N-Term)

Catalog No. ABIN2786652

Product Details anti-Matrilin 3 Antibody

Target: Matrilin 3 (MATN3)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Horse, Zebrafish (Danio rerio), Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Matrilin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ARGAGVCKSR PLDLVFIIDS SRSVRPLEFT KVKTFVSRII DTLDIGPADT

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against MATN3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MATN3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 486 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Matrilin 3 antibody (ABIN2786652)

Fresquet, Jackson, Loughlin, Briggs: "Novel mutations in exon 2 of MATN3 affect residues within the alpha-helices of the A-domain and can result in the intracellular retention of mutant matrilin-3." in: Human mutation, Vol. 29, Issue 2, pp. 330, (2008) (PubMed).

Target Details for Matrilin 3

Target: Matrilin 3 (MATN3)

Alternative Name: MATN3 (MATN3 Products)

Synonyms: DIPOA antibody, EDM5 antibody, HOA antibody, OADIP antibody, OS2 antibody, AV009181 antibody, matrilin 3 antibody, MATN3 antibody, Matn3 antibody

Background: This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two
Alias Symbols: EDM5, HOA, OS2, DIPOA, OADIP
Protein Interaction Partner: NOTCH2NL, KRTAP10-8, TCF4, MATN4, MATN3, MATN1, MATN2,
Protein Size: 486

Molecular Weight: 50 kDa

Gene ID: 4148

NCBI Accession: NM_002381, NP_002372

UniProt: O15232