MMP13 antibody (Middle Region)

Catalog No. ABIN2786656

Cited in 1 publication. The Rabbit Polyclonal anti-MMP13 antibody (ABIN2786656) specifically detects MMP13 in WB. The antibody is reactive with Human, Mouse, Rat, Rabbit, Cow, Horse, Dog, Guinea Pig, Saccharomyces cerevisiae and Sheep samples.

Quick Overview for MMP13 antibody (Middle Region) (ABIN2786656)

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Horse, Dog, Guinea Pig, Saccharomyces cerevisiae, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMP13 Antibody

Binding Specificity: Middle Region

Purpose: MMP13 Antibody - middle region

Sequence: HFMLPDDDVQ GIQSLYGPGD EDPNPKHPKT PDKCDPSLSL DAITSLRGET

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against MMP13. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MMP13

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56350-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-MMP13 antibody (ABIN2786656)

Park, David, Park, Lin, Than, Lee, Park, Jo, Park, Yang: "Controlled release of simvastatin from in situ forming hydrogel triggers bone formation in MC3T3-E1 cells." in: The AAPS journal, Vol. 15, Issue 2, pp. 367-76, (2013) (PubMed).

Target Details for MMP13

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Alternative Name: MMP13

Background:

Background Information: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as art

Gene Name: Matrix metallopeptidase 13 (collagenase 3)

Alternative Symbols: CLG3, MDST, MANDP1, MMP-13

Protein Name: Collagenase 3

Molecular Weight: 42kDa

Gene ID: 4322

NCBI Accession: NP_002418

UniProt: P45452