MYD88 antibody (N-Term)

Catalog No. ABIN2786657

This Rabbit Polyclonal antibody specifically detects MYD88 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for MYD88 antibody (N-Term) (ABIN2786657)

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYD88 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYD88 Antibody

Binding Specificity: N-Term

Sequence: YLEIRQLETQ ADPTGRLLDA WQGRPGASVG RLLELLTKLG RDDVLLELGP

Predicted Reactivity: Dog: 77%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Mouse: 75%, Rabbit: 85%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against MYD88. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYD88

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 296 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYD88

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Alternative Name: MYD88

Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways reg
Alias Symbols: MYD88D
Protein Interaction Partner: MYD88, IRAK4, IL1R1, IKBKG, SPOP, SYK, SASH1, TRAF6, SIAH2, SIAH1, PFKL, PRDX1, MDM2, MAL, SMAD3, MBIP, TLR7, TNFRSF13B, CD93, IKBKE, POLR1C, IL1RL1, FADD, USP7, TXN, BST2, SMURF1, LRRFIP2, UBC, SMAD6, IRF5, IRAK1, BTK, PELI1, STAP2, TNIP1, TRAF3, IRAK2,
Protein Size: 296

Molecular Weight: 33 kDa

Gene ID: 4615

NCBI Accession: NM_002468, NP_002459

UniProt: Q99836

Pathways: NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades