SERPINB2 antibody (Middle Region)

Catalog No. ABIN2786668

There is 1 publication for this product available. The Rabbit Polyclonal anti-SERPINB2 antibody is suitable to detect SERPINB2 in samples from Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Horse, Dog and Sheep. It has been validated for WB.

Quick Overview for SERPINB2 antibody (Middle Region) (ABIN2786668)

Target: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Horse, Dog, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SERPINB2 Antibody

Binding Specificity: Middle Region

Purpose: SERPINB2 Antibody - middle region

Sequence: GKIPNLLPEG SVDGDTRMVL VNAVYFKGKW KTPFEKKLNG LYPFRVNSAQ

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 85%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against SERPINB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SERPINB2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56375-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SERPINB2 antibody (ABIN2786668)

Stutchbury, Al-Ejeh, Stillfried, Croucher, Andrews, Irving, Links, Ranson: "Preclinical evaluation of 213Bi-labeled plasminogen activator inhibitor type 2 in an orthotopic murine xenogenic model of human breast carcinoma." in: Molecular cancer therapeutics, Vol. 6, Issue 1, pp. 203-12, (2007) (PubMed).

Target Details for SERPINB2

Target: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Alternative Name: SERPINB2

Target Type: Amino Acid

Background:

Background Information: SERPINB2 inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.

Gene Name: Serpin peptidase inhibitor, clade B (ovalbumin), member 2

Alternative Symbols: PAI, PAI2, PAI-2, PLANH2, HsT1201

Protein Name: Plasminogen activator inhibitor 2

Molecular Weight: 44kDa

Gene ID: 5055

NCBI Accession: NP_002566

UniProt: P05120

Pathways: Autophagy