Phosphoglucomutase 1 antibody (Middle Region)

Catalog No. ABIN2786673

The Rabbit Polyclonal anti-Phosphoglucomutase 1 antibody (ABIN2786673) specifically detects Phosphoglucomutase 1 in WB. The antibody is reactive with Human, Mouse, Rat, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Cow, Dog, Horse and Goat samples.

Quick Overview for Phosphoglucomutase 1 antibody (Middle Region) (ABIN2786673)

Target: Phosphoglucomutase 1 (PGM1)

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Cow, Dog, Horse, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phosphoglucomutase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Phosphoglucomutase 1 Antibody

Binding Specificity: Middle Region

Purpose: PGM1 Antibody - middle region

Sequence: TVEKADNFEY SDPVDGSISR NQGLRLIFTD GSRIVFRLSG TGSAGATIRL

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 85%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PGM1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PGM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56383-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Phosphoglucomutase 1

Target: Phosphoglucomutase 1 (PGM1)

Alternative Name: PGM1

Background:

Background Information: PGM1 is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90 % of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14.

Gene Name: Phosphoglucomutase 1

Alternative Symbols: CDG1T, GSD14

Protein Name: Phosphoglucomutase-1

Molecular Weight: 61kDa

Gene ID: 5236

NCBI Accession: NP_002624

UniProt: P36871

Pathways: Cellular Glucan Metabolic Process