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PSMB1 antibody (Middle Region)

PSMB1 Reactivity: Human, Mouse, Rat, Rabbit, Saccharomyces cerevisiae, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786714
  • Target See all PSMB1 Antibodies
    PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))
    Binding Specificity
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    Middle Region
    Reactivity
    • 33
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Saccharomyces cerevisiae, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 32
    • 1
    Rabbit
    Clonality
    • 32
    • 1
    Polyclonal
    Conjugate
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMB1 antibody is un-conjugated
    Application
    • 23
    • 19
    • 18
    • 10
    • 6
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    NNKAMTTGAI AAMLSTILYS RRFFPYYVYN IIGGLDEEGK GAVYSFDPVG
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against PSMB1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PSMB1
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    Discover our top product PSMB1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 241 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))
    Alternative Name
    PSMB1 (PSMB1 Products)
    Synonyms
    DDBDRAFT_0217063 antibody, DDBDRAFT_0232957 antibody, DDB_0217063 antibody, DDB_0232957 antibody, AA409053 antibody, C81484 antibody, Lmpc5 antibody, HC5 antibody, PMSB1 antibody, PSC5 antibody, wu:fc51f06 antibody, zgc:103665 antibody, proteasome subunit beta 1 antibody, 20S proteasome subunit beta-1 antibody, proteasome subunit beta type 1 antibody, proteasome (prosome, macropain) subunit, beta type 1 antibody, proteasome subunit beta 1 S homeolog antibody, psmb1 antibody, PSMB1 antibody, psmB1 antibody, LOC100286342 antibody, Psmb1 antibody, psmb1.S antibody
    Background
    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB1 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: FLJ25321, HC5, KIAA1838, PMSB1, PSC5
    Protein Interaction Partner: MAPRE3, UBC, TRAF1, TRIM27, KRT15, KRT13, KIFC3, CDKN1B, PSMA7, HAUS2, PSMD14, PSEN1, PSMG3, PSMB8, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMB2, PSMA6, PSMA5, PSMA4, PSMA3, PSMA1, HNRNPA2B1, DDB2, SMEK1, AP3M1, PSME4, RPP38, RPP30, SEC13, PYCRL, HECW2, PSMA2
    Protein Size: 241
    Molecular Weight
    26 kDa
    Gene ID
    5689
    NCBI Accession
    NM_002793, NP_002784
    UniProt
    P20618
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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