PSMD1 antibody (N-Term)

Catalog No. ABIN2786725

This Rabbit Polyclonal antibody specifically detects PSMD1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit and Pig.It has been mentioned in 1 publication

Quick Overview for PSMD1 antibody (N-Term) (ABIN2786725)

Target: PSMD1 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 1 (PSMD1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSMD1 Antibody

Binding Specificity: N-Term

Sequence: DLYESASQQF LSSVIQNLRT VGTPIASVPG STNTGTVPGS EKDSDSMETE

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PSMD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 953 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PSMD1 antibody (ABIN2786725)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for PSMD1

Target: PSMD1 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 1 (PSMD1))

Alternative Name: PSMD1

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits a
Alias Symbols: MGC133040, MGC133041, P112, S1, Rpn2
Protein Interaction Partner: HUWE1, UBC, SUMO2, SNAI2, PSMD14, TXNL1, PPFIA1, RPS28, RPS21, RPS15A, RPS12, RPS8, UCHL5, ADRM1, PSMD12, PSMD11, PSMD8, PSMD4, PSMD3, PSMD2, PSMC6, PSMC5, PSMC3, PSMC2, PSMC1, PARK2, GSK3A, CDK11A, CDK20, ICK, RNF11, HDAC6, NPM1, PSMB7, SMAD1, HSP90AB1,
Protein Size: 953

Molecular Weight: 106 kDa

Gene ID: 5707

NCBI Accession: NM_002807, NP_002798

UniProt: Q99460

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway