Radixin antibody (Middle Region)

Catalog No. ABIN2786750

The Rabbit Polyclonal anti-Radixin antibody has been validated for WB and IHC. It is suitable to detect Radixin in samples from Human, Mouse, Rat, Cow, Pig, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for Radixin antibody (Middle Region) (ABIN2786750)

Target: Radixin (RDX)

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Radixin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Radixin Antibody

Binding Specificity: Middle Region

Sequence: MSAPPPPPPP PVIPPTENEH DEHDENNAEA SAELSNEGVM NHRSEEERVT

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RDX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RDX

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 583 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Radixin

Target: Radixin (RDX)

Alternative Name: RDX

Background: Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated ver
Alias Symbols: DFNB24
Protein Interaction Partner: UBC, RNF2, ANP32E, RNASEH2B, NSUN2, GSPT2, ATG7, SNX2, LPP, GTF2A1, GSPT1, CTTN, ATP6V1C1, MAPK10, LYN, ESR1, PRDX6, EZR, TRAPPC10, NCL, HNRNPF, BRCA1, ELAVL1, CALM1, PHLPP2, SLC9A3R2, TSC1, SLC9A3R1, GNA13, CPNE4, CPNE2, CPNE1, ARHGDIA, ROCK1, ABCC2, ITG
Protein Size: 583

Molecular Weight: 68 kDa

Gene ID: 5962

NCBI Accession: NM_002906, NP_002897

UniProt: P35241

Pathways: Regulation of Actin Filament Polymerization, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome