MAPK12 antibody (C-Term)

Catalog No. ABIN2786760

This anti-MAPK12 antibody is a Rabbit Polyclonal antibody detecting MAPK12 in WB. Suitable for Human, Mouse, Rat, Rabbit, Guinea Pig, Cow, Horse and Dog.

Quick Overview for MAPK12 antibody (C-Term) (ABIN2786760)

Target: MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Cow, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAPK12 Antibody

Binding Specificity: C-Term

Sequence: ERMLVLDAEQ RVTAAEALTH PYFESLRDTE DEPKAQKYDD SFDDVDRTLE

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Mapk12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 367 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAPK12

Target: MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))

Alternative Name: Mapk12

Background: Mapk12 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Mapk12 plays a role in myoblast differentiation and also in the down-regulation of cyclin D1 in response to hypoxia in adrenal cells suggesting MAPK12 may inhibit cell proliferation while promoting differentiation.
Alias Symbols: AW123708, Erk6, P38gamma, Prkm12, Sapk3
Protein Interaction Partner: Dlg1,
Protein Size: 367

Molecular Weight: 40 kDa

Gene ID: 29857

NCBI Accession: NM_013871, NP_038899

UniProt: O08911

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C, BCR Signaling, S100 Proteins