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MAPK12 antibody (pThr183, pTyr185)

MAPK12 Reactivity: Human WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387757
  • Target See all MAPK12 Antibodies
    MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))
    Binding Specificity
    • 10
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr183, pTyr185
    Reactivity
    • 63
    • 35
    • 11
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 52
    • 8
    • 3
    • 2
    Rabbit
    Clonality
    • 56
    • 9
    Polyclonal
    Conjugate
    • 36
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPK12 antibody is un-conjugated
    Application
    • 52
    • 35
    • 26
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human SAPK3 around the phosphorylation site of Thr183+Tyr185 [EM(p-T)G(p-Y)VV]
    Isotype
    IgG
    Top Product
    Discover our top product MAPK12 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))
    Alternative Name
    SAPK3+ (MAPK12 Products)
    Synonyms
    ATMPK12 antibody, MAPK12 antibody, T3F17.28 antibody, mitogen-activated protein kinase 12 antibody, MGC160082 antibody, si:dkey-14d8.5 antibody, erk6 antibody, etID309866.18 antibody, mapk12 antibody, sapk3 antibody, wu:fa05c12 antibody, zgc:101695 antibody, ERK3 antibody, ERK6 antibody, P38GAMMA antibody, PRKM12 antibody, SAPK-3 antibody, SAPK3 antibody, AW123708 antibody, Erk6 antibody, P38gamma antibody, Prkm12 antibody, Sapk3 antibody, mitogen-activated protein kinase 12 antibody, mitogen-activated protein kinase 12b antibody, mitogen-activated protein kinase 12a antibody, MPK12 antibody, MAPK12 antibody, mapk12b antibody, mapk12a antibody, Mapk12 antibody
    Background

    Synonyms: p-SAPK3Thr183+Tyr185, MAP kinase 12, MAP kinase p38 gamma, MAPK 12, Mapk12, Mitogen Activated Protein Kinase 12, ERK6, ERK 6, ERK-6, Extracellular signal-regulated kinase 6, Mitogen activated protein kinase 3, Mitogen activated protein kinase p38 gamma, Mitogen-activated protein kinase 12, Mitogen-activated protein kinase p38 gamma, MK12_HUMAN, P38 GAMMA, P38GAMMA, PRKM12, SAPK 3, SAPK3, Stress Activated Protein Kinase 3, Stress-activated protein kinase 3.

    Background: MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38 alpha, p38 beta and p38 gamma, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38 alpha, p38 beta and p38 gamma are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.

    Pathways
    MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C, BCR Signaling, S100 Proteins
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