SFRP2 antibody (Middle Region)

Catalog No. ABIN406613

The Rabbit Polyclonal anti-SFRP2 antibody is suitable to detect SFRP2 in samples from Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Sheep and Guinea Pig. It has been validated for WB.

Quick Overview for SFRP2 antibody (Middle Region) (ABIN406613)

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SFRP2 Antibody

Binding Specificity: Middle Region

Sequence: DRFPQDNDLC IPLASSDHLL PATEEAPKVC EACKNKNDDD NDIMETLCKN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against SFRP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SFRP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 295 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SFRP2

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Alternative Name: SFRP2

Background: SFRP2 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FRP-2, SARP1, SDF-5
Protein Interaction Partner: WNT4, PAX2, WNT1, FN1,
Protein Size: 295

Molecular Weight: 31 kDa

Gene ID: 6423

NCBI Accession: NM_003013, NP_003004

UniProt: Q96HF1

Pathways: WNT Signaling, Tube Formation, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Positive Regulation of fat Cell Differentiation