beta-2 Microglobulin antibody (N-Term)

Catalog No. ABIN2786771

This Rabbit Polyclonal antibody specifically detects beta-2 Microglobulin in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, Guinea Pig and Horse.

Quick Overview for beta-2 Microglobulin antibody (N-Term) (ABIN2786771)

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta-2 Microglobulin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-beta-2 Microglobulin Antibody

Binding Specificity: N-Term

Sequence: MSRSVALAVL ALLSLSGLEA IQRTPKIQVY SRHPAENGKS NFLNCYVSGF

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 83%

Characteristics: This is a rabbit polyclonal antibody against B2M. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human B2M

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 119 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for beta-2 Microglobulin

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Alternative Name: B2M

Background: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fib
Alias Symbols: -
Protein Interaction Partner: UBC, CRYAB, B2M, MAPK15, TAP2, HLA-A, HFE, HLA-B, TAPBP, TAP1, GRB2, LILRB1, PRSS23, FCGRT, CD1E, CD1D, CD1A, CD1B, CD8A, HLA-F, HLA-E, HLA-G, HLA-C, BAG6, CALR, A2M,
Protein Size: 119

Molecular Weight: 12 kDa

Gene ID: 567

NCBI Accession: NM_004048, NP_004039

UniProt: P61769

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process