NDUFS3 antibody (Middle Region)

Catalog No. ABIN2786779

This Rabbit Polyclonal antibody specifically detects NDUFS3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Rabbit, Horse, Dog, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for NDUFS3 antibody (Middle Region) (ABIN2786779)

Target: NDUFS3 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (NDUFS3))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Horse, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFS3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NDUFS3 Antibody

Binding Specificity: Middle Region

Sequence: ANHPDLRRIL TDYGFEGHPF RKDFPLSGYV ELRYDDEVKR VVAEPVELAQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against NDUFS3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NDUFS3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 264 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDUFS3

Target: NDUFS3 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (NDUFS3))

Alternative Name: NDUFS3

Background: This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.
Alias Symbols: CI-30
Protein Interaction Partner: HUWE1, UBC, PARK2, ADRB2, ILK, RASL10B, VCAM1, ITGA4, FN1, Htt, NDUFS7, TMEM14C, SAMM50, MRPL3, SURF1, SSBP1, SLC3A2, SDHA, NDUFV2, NDUFS8, NDUFV1, NDUFS2, NDUFA5, PARK7, CUL3, NDUFB6, NDUFA9, ND6, GZMA, MYC, ICT1,
Protein Size: 264

Molecular Weight: 30 kDa

Gene ID: 4722

NCBI Accession: NM_004551, NP_004542

UniProt: O75489

Pathways: Negative Regulation of intrinsic apoptotic Signaling