PTPN14 antibody (N-Term)

Catalog No. ABIN2786811

The Rabbit Polyclonal anti-PTPN14 antibody is suitable to detect PTPN14 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for PTPN14 antibody (N-Term) (ABIN2786811)

Target: PTPN14 (Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTPN14 Antibody

Binding Specificity: N-Term

Sequence: HVQCSEHYSE THTSQDSIFP GNEEALYCRS HNSLDLNYLN GTVTNGSVCS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Ptpn14. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of mouse PTPN14

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTPN14

Target: PTPN14 (Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))

Alternative Name: Ptpn14

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.
Alias Symbols: PEZ, PTP36
Protein Size: 472

Molecular Weight: 51 kDa

Gene ID: 5784

NCBI Accession: NM_005401, NP_005392

UniProt: Q15678