PTPN14 antibody (AA 220-351)

Catalog No. ABIN7174097

Product Details anti-PTPN14 Antibody

Target: PTPN14 (Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))

Binding Specificity: AA 220-351

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN14 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Tyrosine-protein phosphatase non-receptor type 14 protein (220-351AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PTPN14

Target: PTPN14 (Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))

Alternative Name: PTPN14 (PTPN14 Products)

Synonyms: PEZ antibody, PTP36 antibody, C130080N23Rik antibody, OTTMUSG00000022087 antibody, protein tyrosine phosphatase, non-receptor type 14 antibody, PTPN14 antibody, Ptpn14 antibody

Background:

Background: Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor.

Aliases: Cytoskeletal associated protein tyrosine phosphatase antibody, MGC126803 antibody, PEZ antibody, Phosphatase with ezrin domain antibody, Protein tyrosine phosphatase non receptor type 14 antibody, Protein tyrosine phosphatase pez antibody, Protein-tyrosine phosphatase pez antibody, PTN14_HUMAN antibody, PTP 36 antibody, PTP36 antibody, PTPD 2 antibody, PTPN 14 antibody, PTPN14 antibody, Tyrosine protein phosphatase non receptor type 14 antibody, Tyrosine-protein phosphatase non-receptor type 14 antibody

UniProt: Q15678