RHEB antibody (Middle Region)

Catalog No. ABIN2786819

Product Details anti-RHEB Antibody

Target: RHEB (Ras Homolog Enriched in Brain (RHEB))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHEB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VGKVQIPIML VGNKKDLHME RVISYEEGKA LAESWNAAFL ESSAKENQTA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RHEB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RHEB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 184 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RHEB

Target: RHEB (Ras Homolog Enriched in Brain (RHEB))

Alternative Name: RHEB (RHEB Products)

Background: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in
Alias Symbols: MGC111559, RHEB2
Protein Interaction Partner: MTOR, RPS6KB1, PLD1, RPTOR, FKBP8, Appl1, Blzf1, Traf2, ARIH2, UBC, NCAM1, RABAC1, BNIP3L, BNIP3, ECSIT, PSEN2, PSEN1, APOE, A2M, ATR, ATM, PDE6D, TSC2, RAF1, BRAF, RAB9A, RAB7A, TSC1, RAP1A, HRAS, MLST8, BCL2,
Protein Size: 184

Molecular Weight: 20 kDa

Gene ID: 6009

NCBI Accession: NM_005614, NP_005605

UniProt: Q15382

Pathways: RTK Signaling