RHEB antibody (Middle Region)

Catalog No. ABIN2786819

This anti-RHEB antibody is a Rabbit Polyclonal antibody detecting RHEB in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Goat and Zebrafish (Danio rerio).

Quick Overview for RHEB antibody (Middle Region) (ABIN2786819)

Target: RHEB (Ras Homolog Enriched in Brain (RHEB))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHEB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RHEB Antibody

Binding Specificity: Middle Region

Sequence: VGKVQIPIML VGNKKDLHME RVISYEEGKA LAESWNAAFL ESSAKENQTA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RHEB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RHEB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 184 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RHEB

Target: RHEB (Ras Homolog Enriched in Brain (RHEB))

Alternative Name: RHEB

Background: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in
Alias Symbols: MGC111559, RHEB2
Protein Interaction Partner: MTOR, RPS6KB1, PLD1, RPTOR, FKBP8, Appl1, Blzf1, Traf2, ARIH2, UBC, NCAM1, RABAC1, BNIP3L, BNIP3, ECSIT, PSEN2, PSEN1, APOE, A2M, ATR, ATM, PDE6D, TSC2, RAF1, BRAF, RAB9A, RAB7A, TSC1, RAP1A, HRAS, MLST8, BCL2,
Protein Size: 184

Molecular Weight: 20 kDa

Gene ID: 6009

NCBI Accession: NM_005614, NP_005605

UniProt: Q15382

Pathways: RTK Signaling