PDE4D antibody (N-Term)

Catalog No. ABIN2786830

The Rabbit Polyclonal anti-PDE4D antibody is suitable to detect PDE4D in samples from Human, Mouse, Rat, Horse, Cow, Dog, Rabbit and Pig. It has been validated for WB.

Quick Overview for PDE4D antibody (N-Term) (ABIN2786830)

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE4D Antibody

Binding Specificity: N-Term

Purpose: Pde4d Antibody - N-terminal region

Sequence: PFAQVLASLR TVRNNFAALT NLQDRAPSKR SPMCNQPSIN KATITEEAYQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Pde4d. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56672-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE4D

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Alternative Name: Pde4d

Background:

Background Information: Pde4d hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Gene Name: Phosphodiesterase 4D, cAMP specific

Alternative Symbols: Dpde, dunc, Dpde3, 9630011N22Rik

Protein Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Molecular Weight: 84kDa

Gene ID: 238871

NCBI Accession: NP_035186

UniProt: Q01063

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling