GEMIN4 antibody (N-Term)

Catalog No. ABIN2786885

The Rabbit Polyclonal anti-GEMIN4 antibody is suitable to detect GEMIN4 in samples from Human, Mouse, Dog, Rabbit, Cow, Guinea Pig, Horse and Rat. It has been validated for WB.

Quick Overview for GEMIN4 antibody (N-Term) (ABIN2786885)

Target: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Reactivity: Human, Mouse, Dog, Rabbit, Cow, Guinea Pig, Horse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEMIN4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GEMIN4 Antibody

Binding Specificity: N-Term

Sequence: QALAEKVKEA ERDVSLTSLA KLPSETIFVG CEFLHHLLRE WGEELQAVLR

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GEMIN4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GEMIN4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1058 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GEMIN4

Target: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Alternative Name: GEMIN4

Background: The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes requi
Alias Symbols: DKFZP434B131, DKFZP434D174, HC56, HCAP1, HHRF-1, p97
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, BMI1, MIB1, RN7SL1, EGFR, GEMIN4, DICER1, DDX20, SMN1, HDAC11, GLYR1, FLAD1, MORC4, vpr, SRRT, AGO2, PNKP, PIAS3, SPRY1, CALCOCO2, IQCB1, SQSTM1, UBL4A, DMPK, GEMIN2, SRP54, SRP9, RNU2-1, BARD1, RNU1-1, GEMIN5, TOP1, GRK5, SIRT7, SU
Protein Size: 1058

Molecular Weight: 120 kDa

Gene ID: 50628

NCBI Accession: NM_015721, NP_056536

UniProt: Q8WUM5

Pathways: Ribonucleoprotein Complex Subunit Organization