APIP antibody (Middle Region)

Catalog No. ABIN2786905

This Rabbit Polyclonal antibody specifically detects APIP in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio) and Saccharomyces cerevisiae.

Quick Overview for APIP antibody (Middle Region) (ABIN2786905)

Target: APIP (APAF1 Interacting Protein (APIP))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APIP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APIP Antibody

Binding Specificity: Middle Region

Purpose: APIP Antibody - middle region

Sequence: GIKKCTSGGY YRYDDMLVVP IIENTPEEKD LKDRMAHAMN EYPDSCAVLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against APIP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human APIP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56789-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for APIP

Target: APIP (APAF1 Interacting Protein (APIP))

Alternative Name: APIP

Background:

Background Information: APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004 [PubMed 15262985]).

Gene Name: APAF1 interacting protein

Alternative Symbols: APIP2, CGI29, hAPIP, CGI-29, MMRP19

Protein Name: Probable methylthioribulose-1-phosphate dehydratase

Molecular Weight: 27kDa

Gene ID: 51074

NCBI Accession: NP_057041

UniProt: Q96GX9

Pathways: Methionine Biosynthetic Process