BAF53A antibody (Middle Region)

Catalog No. ABIN2786935

Product Details anti-BAF53A Antibody

Target: BAF53A (Actin-Like 6A (BAF53A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAF53A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TVHYEFPNGY NCDFGAERLK IPEGLFDPSN VKGLSGNTML GVSHVVTTSV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ACTL6A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACTL6B

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BAF53A

Target: BAF53A (Actin-Like 6A (BAF53A))

Alternative Name: ACTL6A (BAF53A Products)

Synonyms: ACTL6 antibody, ARPN-BETA antibody, Arp4 antibody, BAF53A antibody, INO80K antibody, 2810432C06Rik antibody, AI851094 antibody, ARP4 antibody, Actl6 antibody, Baf53a antibody, C79802 antibody, baf53a antibody, fb52e06 antibody, fl26e12 antibody, chunp6900 antibody, wu:fb52e06 antibody, wu:fl26e12 antibody, actl6 antibody, MGC75671 antibody, RGD1307747 antibody, ACTL6A antibody, ATARP4 antibody, F15H18.8 antibody, F15H18_8 antibody, actin-related protein 4 antibody, Actin-like protein 4 antibody, CaO19.5623 antibody, actin antibody, actl6a antibody, actl6a.L antibody, arp4 antibody, arpn-beta antibody, ino80k antibody, actin like 6A antibody, actin-like 6A antibody, actin-related protein 4 antibody, Arp4p antibody, actin like 6A S homeolog antibody, ACTL6A antibody, Actl6a antibody, actl6a antibody, ARP4 antibody, actl6a.S antibody

Background: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.
Alias Symbols: ACTL6, BAF53B, arpNalpha
Protein Size: 226

Molecular Weight: 24 kDa

Gene ID: 51412

NCBI Accession: NM_016188, NP_057272

UniProt: O94805

Pathways: Chromatin Binding, Photoperiodism