Actin-Like 6B antibody (Middle Region)

Catalog No. ABIN2786935

The Rabbit Polyclonal anti-Actin-Like 6B antibody is suitable to detect Actin-Like 6B in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Actin-Like 6B antibody (Middle Region) (ABIN2786935)

Target: Actin-Like 6B (ACTL6B)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Actin-Like 6B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Actin-Like 6B Antibody

Binding Specificity: Middle Region

Purpose: ACTL6B Antibody - middle region

Sequence: TVHYEFPNGY NCDFGAERLK IPEGLFDPSN VKGLSGNTML GVSHVVTTSV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ACTL6A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACTL6B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56846-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Actin-Like 6B

Target: Actin-Like 6B (ACTL6B)

Alternative Name: ACTL6B

Background:

Background Information: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.

Gene Name: actin like 6B

Alternative Symbols: ACTL6, DEE76, BAF53B, EIEE76, IDDSSAD, arpNalpha

Protein Name: actin-like protein 6B

Molecular Weight: 24kDa

Gene ID: 51412

NCBI Accession: NP_057272

UniProt: O94805