COPS7A antibody (Middle Region)

Catalog No. ABIN2786958

This Rabbit Polyclonal antibody specifically detects COPS7A in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for COPS7A antibody (Middle Region) (ABIN2786958)

Target: COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS7A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COPS7A Antibody

Binding Specificity: Middle Region

Sequence: NLKKTIKVTT AAAAAATSQD PEQHLTELRE PAPGTNQRQP SKKASKGKGL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against COPS7A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COPS7A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 275 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COPS7A

Target: COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))

Alternative Name: COPS7A

Background: COPS7A is a component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cul
Alias Symbols: MGC110877, CSN7A
Protein Interaction Partner: FBXW11, RAF1, PTGS2, GPS1, UBC, cul1, COPS6, COPS8, PRMT5, WDR77, COPS7B, DCAF8, EPB41L1, COPS4, FBXO6, FBXW4, VCP, DDIT3, COPS5, COPS2, COPS3, LRR1, DCAF11, DDA1, RFWD2, UBD, RBX1, VPRBP, CUL2, CUL3, CUL4A, CUL4B, GRK5, DDB1, DDB2, DCUN1D1, COPS7A, PMF1,
Protein Size: 275

Molecular Weight: 30 kDa

Gene ID: 50813

NCBI Accession: NM_016319, NP_057403

UniProt: Q9UBW8

Pathways: Cell Division Cycle