C11orf73 antibody (N-Term)

Catalog No. ABIN2786965

Product Details anti-C11orf73 Antibody

Target: C11orf73 (Chromosome 11 Open Reading Frame 73 (C11orf73))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C11orf73 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GKPSAIFKIS GLKSGEGSQH PFGAMNIVRT PSVAQIGISV ELLDSLAQQT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against l7Rn6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat l7Rn6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 158 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C11orf73

Target: C11orf73 (Chromosome 11 Open Reading Frame 73 (C11orf73))

Alternative Name: l7Rn6 (C11orf73 Products)

Synonyms: C11orf73 antibody, HSPC179 antibody, Hikeshi antibody, L7RN6 antibody, OPI10 antibody, Hikeshi, heat shock protein nuclear import factor antibody, Hikeshi, heat shock protein nuclear import factor L homeolog antibody, HIKESHI antibody, hikeshi.L antibody, hikeshi antibody, Hikeshi antibody

Background: L7Rn6 acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. It does not translocate ADP-bound HSP70 proteins into the nucleus.
Alias Symbols: -
Protein Size: 158

Molecular Weight: 17 kDa

Gene ID: 293103

NCBI Accession: NM_001013897, NP_001013919

Pathways: Protein targeting to Nucleus