FBXO34 antibody (Middle Region)

Catalog No. ABIN2787049

Product Details anti-FBXO34 Antibody

Target: FBXO34 (F-Box Protein 34 (FBXO34))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Guinea Pig, Mouse, Cow, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO34 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ESECLKRQGQ REPGSLSRNN SFRRNVGRVL LANSTQADEG KTKKGVLEAP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO34. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO34

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 711 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO34

Target: FBXO34 (F-Box Protein 34 (FBXO34))

Alternative Name: FBXO34 (FBXO34 Products)

Synonyms: Fbx34 antibody, 2900057B08Rik antibody, 5830426G16Rik antibody, FBXO34 antibody, F-box protein 34 antibody, F-box protein 34 L homeolog antibody, FBXO34 antibody, Fbxo34 antibody, fbxo34.L antibody, fbxo34 antibody

Background: Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Alias Symbols: CGI-301, DKFZp547C162, FLJ20725, Fbx34, MGC126434, MGC126435
Protein Interaction Partner: KRT40, MTUS2, MDFI, CUL1, UBC, HSP90AA1, TGFBR2, TGFBR1, SKP1, SMAD4,
Protein Size: 711

Molecular Weight: 79 kDa

Gene ID: 55030

NCBI Accession: NM_017943, NP_060413

UniProt: Q9NWN3