Nodal antibody (N-Term)

Catalog No. ABIN2787061

This anti-Nodal antibody is a Rabbit Polyclonal antibody detecting Nodal in WB. Suitable for Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig and Rabbit.

Quick Overview for Nodal antibody (N-Term) (ABIN2787061)

Target: Nodal (NODAL) (Nodal Homolog (NODAL))

Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nodal antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Nodal Antibody

Binding Specificity: N-Term

Sequence: PSSPSPLAYM LSLYRDPLPR ADIIRSLQAE DVAVDGQNWT FAFDFSFLSQ

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NODAL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NODAL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 347 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Nodal

Target: Nodal (NODAL) (Nodal Homolog (NODAL))

Alternative Name: NODAL

Background: The protein encoded by this gene is a member of the TGF-beta superfamily. Studies of the mouse counterpart suggested that this gene may be essential for mesoderm formation and subsequent organization of axial structures in early embryonic development.
Alias Symbols: MGC138230, HTX5
Protein Size: 347

Molecular Weight: 37 kDa

Gene ID: 4838

NCBI Accession: NM_018055, NP_060525

UniProt: Q96S42

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of Endopeptidase Activity