SHQ1 antibody (N-Term)

Catalog No. ABIN2787069

The Rabbit Polyclonal anti-SHQ1 antibody is suitable to detect SHQ1 in samples from Human, Mouse, Rat, Saccharomyces cerevisiae, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for SHQ1 antibody (N-Term) (ABIN2787069)

Target: SHQ1 (SHQ1 Homolog (SHQ1))

Reactivity: Human, Mouse, Rat, Saccharomyces cerevisiae, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHQ1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SHQ1 Antibody

Binding Specificity: N-Term

Purpose: Shq1 Antibody - N-terminal region

Sequence: PYFLRLTLPG RIVENGSEQG TYDADKGIFT IRLPKETPGQ HFEGLNMLTA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against Shq1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Shq1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57120-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SHQ1

Target: SHQ1 (SHQ1 Homolog (SHQ1))

Alternative Name: Shq1

Background:

Background Information: Shq1 is required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA.

Alternative Symbols: Grim, Grim-1, 2810403P18Rik

Protein Name: Protein SHQ1 homolog

Molecular Weight: 50kDa

Gene ID: 72171

NCBI Accession: NP_853621

UniProt: Q7TMX5

Pathways: Ribonucleoprotein Complex Subunit Organization