Acylglycerol Kinase antibody (N-Term)
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- Target See all Acylglycerol Kinase (AGK) Antibodies
- Acylglycerol Kinase (AGK)
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Acylglycerol Kinase antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DNLLRRAACQ EAQVFGNQLI PPNAQVKKAT VFLNPAACKG KARTLFEKNA
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against AGK. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human AGK
- Top Product
- Discover our top product AGK Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 422 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Acylglycerol Kinase (AGK)
- Alternative Name
- AGK (AGK Products)
- Synonyms
- mulk antibody, CATC5 antibody, CTRCT38 antibody, MTDPS10 antibody, MULK antibody, 2610037M15Rik antibody, 6720408I04Rik antibody, AI465370 antibody, Mulk antibody, RGD1562046 antibody, fi38e09 antibody, wu:fi38e09 antibody, zgc:55462 antibody, acylglycerol kinase antibody, acylglycerol kinase S homeolog antibody, AGK antibody, agk antibody, LOC100165096 antibody, Agk antibody, agk.S antibody
- Background
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AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Alias Symbols: FLJ10842, MULK, MTDPS10
Protein Interaction Partner: PCSK9, UBC, RNF2, BMI1, PARK2, FBXO6, UBD, CUL3, AGO4, RYK, ICT1, SNX4, PDLIM1, HCK,
Protein Size: 422 - Molecular Weight
- 47 kDa
- Gene ID
- 55750
- NCBI Accession
- NM_018238, NP_060708
- UniProt
- Q53H12
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